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How Does Hyperparathyroidism Cause Osteoporosis?

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Norman Parathyroid Center
May 30th, 2023

National Osteoporosis Month: Unraveling the Connection - How Does Hyperparathyroidism Cause Osteoporosis?

During National Osteoporosis Month, it is crucial to shed light on the significant impact of parathyroid disease as a leading cause of osteoporosis. In this article, we’ll explore how hyperparathyroidism triggers osteoporosis and emphasize the role of surgery as the only cure for parathyroid disease.

How Does Hyperparathyroidism Cause Osteoporosis? Calcium Imbalance

The interplay between hyperparathyroidism and osteoporosis begins with a disruption of calcium balance. The parathyroid glands, responsible for producing parathyroid hormone (PTH), play a crucial role in regulating calcium levels in the human body. However, in cases of hyperparathyroidism, these glands become overactive, leading to excessive secretion of PTH. This surplus of PTH triggers increased release of calcium from the bones into the bloodstream, resulting in bone loss over time.

How Does Hyperparathyroidism Cause Osteoporosis? Accelerated Bone Resorption

Hyperparathyroidism accelerates bone resorption, a process that leads to decreased bone density. The elevated levels of PTH stimulate the activity of osteoclasts, which break down bone tissue. The overactive osteoclasts surpass the normal bone remodeling process, causing a net loss of bone mass and weakening of the skeletal structure.

How Does Hyperparathyroidism Cause Osteoporosis? Impaired Bone Formation

In addition to excessive bone resorption, hyperparathyroidism can impair bone formation. PTH affects the function of osteoblasts, which are responsible for building new bone tissue. Prolonged elevation of PTH levels may hinder osteoblast activity, reducing their ability to generate new bone. This imbalance between bone resorption and formation further contributes to the development of osteoporosis.

How Does Hyperparathyroidism Cause Osteoporosis? Calcium and Vitamin D Deficiencies

Hyperparathyroidism can also lead to deficiencies in calcium and vitamin D, both essential for maintaining optimal bone health. Excessive PTH levels increase urinary calcium excretion, potentially depleting the body's calcium stores. Additionally, PTH interferes with the conversion of vitamin D into its active form, necessary for proper calcium absorption. Calcium and vitamin D deficiencies exacerbate the detrimental effects of hyperparathyroidism on bone density and integrity.

Parathyroid Surgery is the Only Cure for Parathyroid Disease Causing Osteoporosis

When it comes to parathyroid disease, parathyroid surgery is the only definitive cure. Parathyroid surgery, also known as parathyroidectomy, involves the removal of the affected parathyroid gland(s) responsible for the excessive production of PTH. By addressing the underlying hyperparathyroidism, surgery helps restore calcium balance, improve bone density, and mitigate the progression of osteoporosis. It offers long-term relief and the potential for significant improvements in bone health.

Parathyroid surgery can be a very tricky procedure with debilitating consequences if performed by an inexperienced surgeon. If all four glands are not properly checked, it can lead to an incomplete surgery that will not improve a patient’s osteoporosis and will require additional operations in the future. Worse, if all four glands are removed or damaged, it can lead to hypoparathyroidism for which there is no cure. That’s why it’s so important to seek an expert in parathyroid surgeon the first time. About 25% of our business represent reoperations, where our surgeons are correcting a surgery done elsewhere. Don’t make a mistake with your health!

Conclusion

During National Osteoporosis Month, it is essential to recognize the substantial impact of parathyroid disease on the development of osteoporosis. Hyperparathyroidism disrupts calcium balance, leading to accelerated bone resorption and impaired bone formation. Calcium and vitamin D deficiencies further worsen the effects on bone health.

Parathyroid surgery is the only cure for parathyroid disease. By addressing the underlying hyperparathyroidism, surgery offers the potential to restore calcium balance, reverse bone loss, and halt the progression of osteoporosis. In experienced hands, parathyroid surgery is a minimally invasive, outpatient procedure with practically no downtime. The parathyroid surgeons of the Norman Parathyroid Center, operating at the Hospital for Endocrine Surgery, perform parathyroid surgery exclusively. In fact, they perform nearly 3500 parathyroid operations every year.

National Osteoporosis Month serves as a reminder to prioritize bone health and seek the necessary care to mitigate the impact of parathyroid disease on osteoporosis.

If you suspect that you may have hyperparathyroidism, schedule your consultation with one of our expert parathyroid surgeons to discuss the details of your case. We operate exclusively at the Hospital for Endocrine Surgery in Tampa, Florida. If you are not local to Tampa, no worries! More than half of our patients travel from outside the state of Florida, and 10% even come from foreign countries. We are well versed in making the process seamless for our traveling patients and will cure your parathyroid disease in just one day.

Don’t just take our word for it—check out hundreds of patient testimonials.


  • Additional Resources:

    • Learn more about the Norman Parathyroid Center.
    • Read more on the Parathyroid blog.
    • Become our patient.
    • Check out our sister surgeons at the Clayman Thyroid Center, the Scarless Thyroid Surgery Center and the Carling Adrenal Center. We are now united under one roof, operating at the Hospital for Endocrine Surgery. 

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Author

Norman Parathyroid Center

Located in Tampa, Florida, the Norman Parathyroid Center is the leading parathyroid gland tumor treatment center in the world, performing nearly 3,800 parathyroid operations annually. Well known for cure rates over 99% via an operation that typically lasts about 20 minutes, the Norman Parathyroid Center's success centers on a teamwork approach by the most experienced parathyroid surgeons in the world.
Located in Tampa, Florida, the Norman Parathyroid Center is the leading parathyroid gland tumor treatment center in the world, performing nearly 3,800 parathyroid operations annually. Well known for cure rates over 99% via an operation that typically lasts about 20 minutes, the Norman Parathyroid Center's success centers on a teamwork approach by the most experienced parathyroid surgeons in the world.
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